KMID : 0604520200460030283
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Journal of the Society of Cosmetic Scientists of Korea 2020 Volume.46 No. 3 p.283 ~ p.294
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Antioxidant, Anti-inflammatory and Anti-allergenic Effects of Citrus Junos seed Oil and its Human Skin Protection
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Ko Eun-Ah
Nam Seung-Hee Jeong Ha-na Kim Bo-Yun Kwak Sang-Hwa Kim Sun-Young Hong In-Ki Kang Hak-Hee
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Abstract
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In this study, in order to increase the utilization of Citrus junos seeds, which account for 13% of the weight ratio of Citrus junos ripened fruit, but are mostly discarded and not utilized, the efficacy of skin beauty of Citrus junos seed oil extracted by cold pressing was studied. Citrus junos seed oil was found to contain approximately 74% of unsaturated fatty acids consisting mainly of oleic acid and linoleic acid, and limonene, which is mainly contained in Citrus junos peel, contained a very low content of about 0.0187%. As a result of evaluating the DPPH radical scavenging activity of Citrus junos seed oil, 26% of DPPH radical scavenging ability was confirmed at 5% concentration of Citrus junos seed oil. To confirm the anti-inflammatory effect, as a result of testing RAW 264.7 cytotoxicity test and NO production for Citrus junos seed oil, NO production was suppressed by 53% at a concentration of 0.05% that does not show cytotoxicity. In addition, in the RBL-2H3 cytotoxicity and ¥â-hexosaminidase release inhibitory efficacy test for anti-allergic efficacy confirmation, it was confirmed that ¥â-hexosaminidas release was suppressed by 26% at a concentration of 0.05% that did not show cytotoxicity. Lastly, in the human skin application test result of O/W emulsion containing 5% of Citrus junos seed oil, it showed higher skin moisturizing effect than the control emulsion containing the same amount of caprylic/capric triglyceride. Therefore, it is thought that Citrus junos seed oil might be used as a excellent skin care material.
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KEYWORD
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Citrus junos, unsaturated fatty acid, anti-inflammation, anti-allergy, moisturization
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